The Complete List of Top Fortune 500 Companies Using AWS in USA (Updated 2025)

What is Amazon Web Services (AWS)?

As the world’s most comprehensive and broadly adopted cloud computing platform, Amazon Web Services (AWS) is offering over 200 fully featured services from data centers globally. Launched in 2006, AWS has revolutionized how businesses operate by providing on-demand access to computing resources, storage, databases, analytics, machine learning, and more. Serving millions of customers, from innovative startups to large enterprises and government agencies, this cloud infrastructure giant enables them to scale and grow more efficiently than ever before.

AWS Products and Services

  • Compute Services: Amazon EC2 (Elastic Compute Cloud, AWS Lambda, Amazon ECS (Elastic Container Service)
  • Storage Services: Amazon S3 (Simple Storage Service), Amazon EBS (Elastic Block Store), Amazon Glacier
  • Database Services: Amazon RDS (Relational Database Service), Amazon DynamoDB, Amazon Redshift, Machine Learning and AI, Amazon SageMaker, Amazon Rekognition, Amazon Comprehend.
  • Analytics Services: Amazon Kinesis, AWS Glue, Amazon QuickSight
  • Security and Identity Services: AWS Identity and Access Management (IAM): AWS Shield, AWS Certificate Manager

Key Features of AWS

  • Global Infrastructure
  • Scalability and Elasticity
  • Security and Compliance
  • Cost Optimization
  • Innovation and Agility
  • Reliability and Availability

Benefits of AWS for Enterprise Organizations

  • Enhanced Business Agility
  • Improved Security Posture
  • Operational Excellence
  • Global Reach and Local Presence
  • Innovation Acceleration
  • Talent and Skills Development

Key Reasons Why Fortune 500 Companies Choose AWS

  • Proven Scale and Reliability
  • Comprehensive Service Portfolio
  • Security and Compliance Leadership
  • Innovation Velocity
  • Cost Optimization Opportunities
  • Talent and Ecosystem Support

Top Companies Using AWS in USA

Apple Inc.

Apple

Fortune 500 Ranking: #4 | Revenue: $383 billion | Industry: Technology Hardware Headquarters: Cupertino, California | Employees: 161,000+

While Apple might be Amazon’s biggest competitors in various technology sectors, paradoxically it is one of AWS’s largest customers. The tech giant spends over $360 million annually on AWS services, primarily leveraging the cloud platform for iCloud services, data storage, and content delivery. Apple uses Amazon S3 for massive-scale object storage, supporting billions of iCloud users worldwide. The company also utilizes AWS’s global infrastructure to ensure fast, reliable access to services across different geographic regions.

Apple’s relationship with AWS demonstrates the pragmatic approach many large technology companies that use AWS take toward cloud infrastructure. Rather than building every capability in-house, Apple focuses on its core competencies while leveraging AWS’s expertise in cloud infrastructure. This partnership allows Apple to scale its services rapidly while maintaining the reliability and performance standards its users expect.

Netflix Inc.

Netflix Inc.

Fortune 500 Ranking: #115 | Revenue: $33.7 billion | Industry: Entertainment Headquarters: Los Gatos, California | Employees: 13,000+

With arguably one of the most successful cloud-native transformations in business history, Netflix has established a cult of its own. Alright. But, even this streaming giant operates entirely on AWS, running hundreds of applications across more than 100,000 server instances. Netflix uses virtually every major AWS service, from compute and storage to advanced analytics and machine learning capabilities.

The company leverages AWS’s global infrastructure to deliver content to over 260 million subscribers worldwide. Netflix uses Amazon CloudFront for content delivery, ensuring users experience minimal buffering regardless of their location. The company also employs AWS’s machine learning services to power its recommendation engine, which drives over 80% of viewer engagement on the platform.

Netflix’s microservices architecture on AWS enables rapid innovation and deployment of new features. The company can test new functionalities with specific user segments and scale successful features globally within hours. This agility has been crucial to Netflix’s ability to compete with other streaming services and maintain its market leadership.

The Walt Disney Company

Fortune 500 Ranking: #55 | Revenue: $82.7 billion | Industry: Entertainment Headquarters: Burbank, California | Employees: 220,000+

Walt Disney Company

Another prominent historical moment was created in 2019, when media heavy-weight Disney choose AWS’s robust platform to launch its popular app — Disney+. The streaming service uses over 50 AWS technologies, including database, storage, machine learning, content delivery, serverless, and analytics services. Disney’s cloud-first approach enabled the platform to handle over 10 million new subscriber sign-ups within 24 hours of launch, demonstrating the scalability of AWS infrastructure.

Beyond streaming, Disney uses AWS across its entertainment empire, from theme park operations to content production. The company leverages AWS’s media services for video processing and content distribution, ensuring high-quality streaming experiences across all Disney properties. Disney also uses AWS machine learning services for content recommendation and customer personalization across its various platforms.

Comcast Corporation

Comcast Corporation

Fortune 500 Ranking: #26 | Revenue: $121.4 billion | Industry: Telecommunications/Media Headquarters: Philadelphia, Pennsylvania | Employees: 186,000+

One of America’s largest telecommunications and media conglomerates — Comcast has AWS as the backbone of its streaming services, including Xfinity TV and Movies & TV Shows on Demand. The company employs AWS in a hybrid environment to innovate and scale its video products rapidly.

Comcast utilizes Amazon Virtual Private Cloud (VPC) and Amazon Direct Connect to create secure, high-performance connections between its on-premises infrastructure and AWS services. This hybrid approach allows Comcast to maintain control over sensitive customer data while leveraging AWS’s scalability for peak demand periods.

The company also uses AWS’s content delivery network services to ensure smooth streaming experiences for millions of customers across the United States. By leveraging AWS’s global infrastructure, Comcast can deliver content with low latency and high availability, crucial factors in the competitive streaming market.

Johnson & Johnson

Johnson & Johnson

Fortune 500 Ranking: #36 | Revenue: $85.2 billion | Industry: Pharmaceuticals/Healthcare Headquarters: New Brunswick, New Jersey | Employees: 152,700+

J&J is mammoth in the healthcare space. And, as one of the world’s largest healthcare companies, even it has embraced AWS as part of its global digital transformation strategy. The pharmaceutical giant uses AWS Cloud for its big data architecture, enabling complex data modeling and analytics across its research and development operations.

The company runs approximately 120 applications on AWS, supporting everything from drug discovery to supply chain management. J&J leverages AWS’s machine learning capabilities to accelerate pharmaceutical research, using predictive analytics to identify promising drug compounds and optimize clinical trial designs.

Johnson & Johnson also uses AWS for regulatory compliance and data security, crucial requirements in the heavily regulated pharmaceutical industry. The company benefits from AWS’s HIPAA-compliant services and robust security features to protect sensitive patient data and proprietary research information.

Pfizer Inc.

Fortune 500 Ranking: #64 | Revenue: $58.5 billion | Industry: Pharmaceuticals Headquarters: New York City, New York | Employees: 83,000+

The pharma giant Pfizer has also adopted AWS as its primary public cloud platform, planning to shift multiple services from internal data centers to AWS infrastructure. This migration is expected to generate productivity gains and cost savings of up to $225 million over time.

The pharmaceutical company uses AWS for clinical manufacturing operations, incorporating predictive maintenance capabilities built using AWS machine learning services. This approach helps Pfizer optimize its manufacturing processes and reduce downtime, crucial factors in pharmaceutical production where consistency and reliability are paramount.

Pfizer also leverages AWS for research and development activities, using the platform’s high-performance computing capabilities for drug discovery and clinical trial management. The company’s COVID-19 vaccine development benefited from AWS’s ability to scale computational resources rapidly, enabling faster research and analysis cycles.

Bristol Myers Squibb

Fortune 500 Ranking: #114 | Revenue: $45.0 billion | Industry: Pharmaceuticals Headquarters: New York City, New York | Employees: 34,300+

Bristol Myers Squibb was the first pharmaceutical company in the world to operate completely on high-performance computing using AWS. This cloud-first approach has enabled the company to make decisions faster and develop therapies more efficiently.

Since adopting AWS in 2015, Bristol Myers Squibb has reduced its data storage needs by 40% while significantly improving computational performance. The company uses AWS for complex molecular modeling, clinical trial analysis, and drug discovery processes that require massive computational power.

The pharmaceutical company leverages AWS’s global infrastructure to collaborate with research partners worldwide, sharing data and insights securely across different geographic regions. This global connectivity has accelerated Bristol Myers Squibb’s research timelines and improved collaboration with academic and industry partners.

Capital One Financial Corporation

Capital One

Fortune 500 Ranking: #102 | Revenue: $38.4 billion | Industry: Financial Services Headquarters: McLean, Virginia | Employees: 52,000+

Capital One stands out as one of the most successful cloud-first transformations in the financial services industry. The bank uses AWS services extensively, including Amazon S3 for data storage and machine learning services for fraud detection and customer analytics.

The financial institution leverages AWS to convert vast amounts of data into actionable insights, using machine learning algorithms to personalize customer experiences and improve risk management. Capital One’s mobile banking platform, which serves millions of customers, runs entirely on AWS infrastructure.

Capital One has also been a pioneer in using AWS for regulatory compliance and risk management in the financial sector. The company demonstrates how traditional banks can successfully migrate to cloud infrastructure while maintaining the security and compliance standards required in financial services.

Bank of America

Bank of America

Fortune 500 Ranking: #29 | Revenue: $94.9 billion | Industry: Financial Services Headquarters: Charlotte, North Carolina | Employees: 216,823+

Bank of America, one of the world’s largest financial institutions, uses AWS for various digital banking initiatives and customer service improvements. The bank leverages AWS’s machine learning capabilities to power its virtual assistant “Erica,” which serves millions of customers through mobile and online banking platforms.

The financial giant uses AWS for data analytics and risk management, processing millions of transactions daily through cloud-based systems. Bank of America’s mobile banking platform, used by over 40 million active users, relies on AWS infrastructure for scalability and reliability.

Bank of America also utilizes AWS for fraud detection and cybersecurity, using machine learning algorithms to identify suspicious activities and protect customer accounts. The bank’s investment in cloud technology has enabled it to offer innovative digital banking services while maintaining industry-leading security standards.

Ford Motor Company

Fortune 500 Ranking: #21 | Revenue: $176.2 billion | Industry: Automotive Headquarters: Dearborn, Michigan | Employees: 173,000+

Ford Motor Company has partnered with AWS to accelerate its transformation into a mobility company. The automaker uses AWS’s global infrastructure and comprehensive service portfolio, including machine learning, analytics, Internet of Things (IoT), and computing services.

Ford leverages AWS for connected vehicle services, using IoT capabilities to collect and analyze data from millions of vehicles on the road. This data helps Ford improve vehicle performance, predict maintenance needs, and develop new mobility services for customers.

The company also uses AWS for manufacturing optimization, employing machine learning algorithms to improve production efficiency and quality control. Ford’s partnership with AWS supports its electric vehicle strategy, using cloud-based analytics to optimize battery performance and charging infrastructure.

McDonald’s Corporation

McDonald's Corporation

Fortune 500 Ranking: #69 | Revenue: $25.5 billion | Industry: Food Services Headquarters: Chicago, Illinois | Employees: 150,000+

McDonald’s Corporation uses AWS to power its digital transformation and global delivery platform. The fast-food giant built its Home Delivery platform using AWS microservices architecture, integrating local restaurants with delivery partners like Uber Eats and DoorDash.

Using Amazon Elastic Container Service, Application Load Balancer, Amazon ElastiCache, and other AWS services, McDonald’s launched its delivery platform within four months. The system now handles millions of orders globally, demonstrating the scalability and reliability of AWS infrastructure.

McDonald’s also uses AWS for customer analytics and personalization, leveraging machine learning to optimize menu recommendations and marketing campaigns. The company’s mobile app, which serves millions of customers worldwide, runs on AWS infrastructure to ensure consistent performance across different geographic regions.

Kellogg Company

Fortune 500 Ranking: #185 | Revenue: $13.6 billion | Industry: Food Products Headquarters: Battle Creek, Michigan | Employees: 23,000+

Kellogg’s has embraced AWS for its worldwide operations and data center management. The food manufacturer uses AWS to support its global supply chain operations, from ingredient sourcing to product distribution across more than 180 countries.

The company leverages AWS analytics services to optimize manufacturing processes and reduce waste. Kellogg’s uses machine learning algorithms to predict demand patterns and adjust production schedules accordingly, helping the company maintain optimal inventory levels while minimizing costs.

Kellogg’s also uses AWS for digital marketing and customer engagement initiatives. The company’s e-commerce platforms and direct-to-consumer channels rely on AWS infrastructure to handle traffic spikes and provide personalized shopping experiences for customers.

General Electric

General Electric

Fortune 500 Ranking: #47 | Revenue: $67.1 billion | Industry: Industrial Equipment Headquarters: Boston, Massachusetts | Employees: 172,000+

General Electric has named AWS as its preferred cloud provider, focusing on industrial Internet of Things (IoT) applications and digital transformation initiatives. GE uses AWS to power its Predix platform, which provides predictive analytics and maintenance services for industrial equipment.

The industrial giant leverages AWS’s machine learning and analytics capabilities to optimize the performance of turbines, locomotives, and other industrial equipment. By analyzing data from thousands of sensors, GE can predict equipment failures before they occur, reducing downtime and maintenance costs for customers.

GE also uses AWS for its healthcare and aviation divisions, supporting medical imaging systems and flight management applications. The company’s partnership with AWS enables GE to offer cloud-based services to customers across various industries, from healthcare to energy.

Adobe Inc.

Adobe Inc.

Fortune 500 Ranking: #167 | Revenue: $21.5 billion | Industry: Software Headquarters: San Jose, California | Employees: 29,239+

Adobe uses AWS to power its Creative Cloud platform, serving millions of creative professionals worldwide. The company leverages AWS’s global infrastructure to deliver software services and store creative assets for users across different geographic regions.

Adobe’s Experience Cloud, which provides marketing and analytics solutions for businesses, runs entirely on AWS infrastructure. The platform processes billions of data points daily, using AWS’s machine learning services to provide personalized customer experiences and marketing insights.

The software company also uses AWS for artificial intelligence and machine learning development, powering features like content-aware fill in Photoshop and automated video editing in Premiere Pro. Adobe’s partnership with AWS enables the company to innovate rapidly and deliver new features to millions of users worldwide.

Current AWS Market Statistics and Trends (2025)

  • Market Share and Revenue: In 2025, AWS market share accounts for 30% of the global cloud infrastructure market, maintaining its position as the leading cloud service provider. AWS statistics show that by 2024, AWS had grossed more than US$107 billion in net sales revenue, representing a significant portion of Amazon’s overall business success.
  • Enterprise Adoption Trends: Flexera’s 2025 State of the Cloud Report shows 81% of enterprises use Azure, slightly more than the 79% that use AWS, indicating strong competition in the enterprise market. However, many organizations use multiple cloud providers, and AWS continues to lead in overall market share and revenue.

Future Outlook: AWS and Fortune 500 Companies

  • Artificial Intelligence Integration: As artificial intelligence becomes increasingly important for business competitiveness, Fortune 500 companies using AWS are turning to the platform’s comprehensive AI and machine learning services. The platform’s ability to handle the massive computational requirements of AI workloads makes it an attractive choice for large-scale AI deployments.
  • Edge Computing Expansion: With the growth of IoT devices and the need for low-latency applications, AWS’s edge computing services are becoming increasingly important for Fortune 500 companies. Services like AWS Wavelength and Local Zones bring cloud capabilities closer to end-users, enabling new types of applications and services.

Conclusion

The adoption of Amazon Web Services by Fortune 500 companies represents a fundamental shift in how large enterprises approach technology infrastructure. This comprehensive list of companies using AWS – from Apple’s massive iCloud operations to Netflix’s global streaming platform – demonstrates that cloud-first strategies can drive innovation, reduce costs, and improve operational efficiency at scale.

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